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  "author": "Dynalife WG4",
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  "author": "Dynalife WG4",
            
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  "creator_user_id": "72b55722-792b-4c74-a9a9-dbe24f5a9386",
            
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  "doi": "10.71802/n3m8o427",
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  "doi": "10.71802/n3m8o427",
            
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  "doi_date_published": null,
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  "doi_date_published": "2025-12-13",
            
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  "doi_publisher": "Dalia - Dati Aperti bibLIoteca Area bologna",
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  "doi_publisher": "Dalia - Dati Aperti bibLIoteca Area bologna",
            
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  "domain": "https://dalia-bo.cnr.it",
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  "domain": "https://dalia-bo.cnr.it",
            
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  "license_id": "notspecified",
            
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  "license_title": "Licenza non specificata",
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  "license_title": "Licenza non specificata",
            
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  "maintainer": "Martina Di Ciano; Gabriela Carrara (Biblioteca Dario 
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  "maintainer": "Martina Di Ciano; Gabriela Carrara (Biblioteca Dario 
            
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Nobili CNR ATdR-BO)",
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Nobili CNR ATdR-BO)",
            
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  "maintainer_email": "dalia-bo@area.bo.cnr.it",
            
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  "name": "2025_2026_dynalife_sozopol_workshop",
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  "name": "2025_2026_dynalife_sozopol_workshop",
            
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  "notes": "This workshop will explore biological information through 
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  "notes": "This workshop will explore biological information through 
            
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its dual nature: \"digital\" and \"analog.\" These distinct modes of 
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its dual nature: \"digital\" and \"analog.\" These distinct modes of 
            
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information processing in biological systems are deeply 
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information processing in biological systems are deeply 
            
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interconnected, collectively contributing to the regulation and 
24
interconnected, collectively contributing to the regulation and 
            
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functioning of living organisms. The \"digital\" aspect refers to 
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functioning of living organisms. The \"digital\" aspect refers to 
            
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genomic sequences \u2014a linear, discrete coding system in DNA that 
26
genomic sequences \u2014a linear, discrete coding system in DNA that 
            
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operates via precise, rule-based codes (e.g., nucleotide sequences 
27
operates via precise, rule-based codes (e.g., nucleotide sequences 
            
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encoding proteins). This structure enables robust, error-corrected 
28
encoding proteins). This structure enables robust, error-corrected 
            
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transmission of genetic information, allowing small, discrete units 
29
transmission of genetic information, allowing small, discrete units 
            
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(genes) to be read, replicated, and passed on with high fidelity. 
30
(genes) to be read, replicated, and passed on with high fidelity. 
            
31
Conversely, \"analog\" information arises from dynamic, continuous 
31
Conversely, \"analog\" information arises from dynamic, continuous 
            
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processes, particularly within signal-transduction pathways and 
32
processes, particularly within signal-transduction pathways and 
            
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cellular interactions. These pathways relay information in a graded 
33
cellular interactions. These pathways relay information in a graded 
            
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manner, modulating responses to environmental stimuli, stress, or 
34
manner, modulating responses to environmental stimuli, stress, or 
            
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internal changes. The workshop seeks to advance understanding of 
35
internal changes. The workshop seeks to advance understanding of 
            
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biological information by emphasizing its dual nature and fostering 
36
biological information by emphasizing its dual nature and fostering 
            
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synergy between theoretical and experimental perspectives.\r\n\r\nKey 
37
synergy between theoretical and experimental perspectives.\r\n\r\nKey 
            
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questions include:\r\n\r\n- How do theoretical models capture the 
38
questions include:\r\n\r\n- How do theoretical models capture the 
            
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interaction between digital genomic information and analog signal 
39
interaction between digital genomic information and analog signal 
            
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transduction pathways?\r\n- Can a unified framework be developed to 
40
transduction pathways?\r\n- Can a unified framework be developed to 
            
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account for both types of information processing?\r\n- How do findings 
41
account for both types of information processing?\r\n- How do findings 
            
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in gene regulation, signaling networks, and epigenetics refine 
42
in gene regulation, signaling networks, and epigenetics refine 
            
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existing models of biological information?\r\n- What roles do noise, 
43
existing models of biological information?\r\n- What roles do noise, 
            
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stochasticity, and robustness play in these processes?\r\n\r\n\r\nThe 
44
stochasticity, and robustness play in these processes?\r\n\r\n\r\nThe 
            
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workshop will highlight the potential of interdisciplinary 
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workshop will highlight the potential of interdisciplinary 
            
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collaborative research in addressing societal challenges, including AI 
46
collaborative research in addressing societal challenges, including AI 
            
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development and applications, as well as public health, among other 
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development and applications, as well as public health, among other 
            
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areas. These contributions aim to bridge the gap between research and 
48
areas. These contributions aim to bridge the gap between research and 
            
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real-world application, inspiring and motivating younger participants 
49
real-world application, inspiring and motivating younger participants 
            
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to pursue this complex and impactful career path.\r\n\r\n__Dates:__ 
50
to pursue this complex and impactful career path.\r\n\r\n__Dates:__ 
            
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4-5 September 2025 \r\n\r\n__Venue:__ Sozopol, Bulgaria, Hotel Villa 
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4-5 September 2025 \r\n\r\n__Venue:__ Sozopol, Bulgaria, Hotel Villa 
            
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List\r\n\r\n__Scientific Committee:__ Nevena Ilieva, Oreste Piro, 
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List\r\n\r\n__Scientific Committee:__ Nevena Ilieva, Oreste Piro, 
            
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Julyan Cartwright\r\n\r\n__Local Organizing  Committee:__ Nevena 
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Julyan Cartwright\r\n\r\n__Local Organizing  Committee:__ Nevena 
            
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Ilieva, Elena Lilkova",
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Ilieva, Elena Lilkova",
            
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